Bioethics today has become a subject of wide public concern. Almost every one of its tenets is being seriously questioned and likely to be reformulated. Moreover, the pressure on bioethics continues to mount as the number of moral conflicts that buffet our society increases. What, then, will bioethics look like a decade from now? In the variety of approaches that have been employed in the practice of bioethics, one has dominated in the United States in the last decade and a (...) half. That approach is "principlism", the use of moral principles to address theoretical issues and to resolve conflicts at the bedside. Recently, however, bioethicists and others increasingly have realized the limitations of principlism and are calling for the development of alternative approaches such as phenomenology, hermeneutics, narrative ethics, casuistry, and virtue ethics. This book maps the debate over principlism and the future direction of U.S. bioethics. Part One consists of a sociological description of U.S. bioethics at the beginning of the 1990s, along with a defense of principlism by one of its major proponents. Part Two maps cross-cultural critiques of principlism, while Part Three covers five alternatives to it. Three essays in Part Four - by a bioethicist, a physician, and a theologian - reflect on the future of U.S. bioethics, principlism, and its alternatives. The Afterword emphasizes the place of religion and theological discourse in the alternative approaches and in the future of bioethics. (shrink)

Volume 20, Issue 10, October 2020, Page 1-4.

We hypothesize that aspects of animal multicellularity originated before the divergence of metazoans from fungi and social amoebae. Polarized epithelial tissues are a defining feature of metazoans and contribute to the diversity of animal body plans. The recent finding of a polarized epithelium in the non‐metazoan social amoeba Dictyostelium discoideum demonstrates that epithelial tissue is not a unique feature of metazoans, and challenges the traditional paradigm that multicellularity evolved independently in social amoebae and metazoans. An alternative view, presented here, is (...) that the common ancestor of social amoebae, fungi, and animals spent a portion of its life cycle in a multicellular state and possessed molecular machinery necessary for forming an epithelial tissue. Some descendants of this ancestor retained multicellularity, while others reverted to unicellularity. This hypothesis makes testable predictions regarding tissue organization in close relatives of metazoans and provides a novel conceptual framework for studies of early animal evolution.Editor's suggested further reading in BioEssays Searching for Eve: Basal metazoans and the evolution of multicellular complexity Abstract. (shrink)

Interspecific comparisons reveal remarkable diversity in patterns of gene expression, even among closely related species. Combinatorial regulatory mechanisms could facilitate the evolution of this diversity. However, the high degree of interdependence characteristic of combinatorial networks would represent a major constraint on evolution and might generate many features that have no direct adaptive value.

Since the first edition was published in 1989, Character and Cops has been considered the bible of police ethics training.

Earlier, we have studied computations possible by physical systems and by algorithms combined with physical systems. In particular, we have analysed the idea of using an experiment as an oracle to an abstract computational device, such as the Turing machine. The theory of composite machines of this kind can be used to understand (a) a Turing machine receiving extra computational power from a physical process, or (b) an experimenter modelled as a Turing machine performing a test of a known physical (...) theory T. Our earlier work was based upon experiments in Newtonian mechanics. Here we extend the scope of the theory of experimental oracles beyond Newtonian mechanics to electrical theory. First, we specify an experiment that measures resistance using a Wheatstone bridge and start to classify the computational power of this experimental oracle using non-uniform complexity classes. Secondly, we show that modelling an experimenter and experimental procedure algorithmically imposes a limit on our ability to measure resistance by the Wheatstone bridge. The connection between the algorithm and physical test is mediated by a protocol controlling each query, especially the physical time taken by the experimenter. In our studies we find that physical experiments have an exponential time protocol, this we formulate as a general conjecture. Our theory proposes that measurability in Physics is subject to laws which are co-lateral effects of the limits of computability and computational complexity. (shrink)

Decision-making regarding treatment for newborns with disabilities in resource-poor settings is a difficult process that can put parents and caregivers in conflict. Despite several guidelines that have helped to clarify some of the medical decision-making in Ghana, there is still no clear consensus on the specific moral criteria to be used. This article presents the case of a mother who expressed her wish that her child with Down syndrome should not have been resuscitated at birth. It explores the ethical issues (...) at stake in both her misgivings about the resuscitation and her unwillingness to consider surgical repair of an atrioventricular (AV) canal defect. Knowing that children born with Down syndrome are able to pursue life’s goals, should our treatment of complete AV canal defect in such children be considered morally obligatory, even in resource-poor settings like Ghana? (shrink)

Earlier, we have studied computations possible by physical systems and by algorithms combined with physical systems. In particular, we have analysed the idea of using an experiment as an oracle to an abstract computational device, such as the Turing machine. The theory of composite machines of this kind can be used to understand (a) a Turing machine receiving extra computational power from a physical process, or (b) an experimenter modelled as a Turing machine performing a test of a known physical (...) theory T.Our earlier work was based upon experiments in Newtonian mechanics. Here we extend the scope of the theory of experimental oracles beyond Newtonian mechanics to electrical theory. First, we specify an experiment that measures resistance using a Wheatstone bridge and start to classify the computational power of this experimental oracle using non-uniform complexity classes. Secondly, we show that modelling an experimenter and experimental procedure algorithmically imposes a limit on our ability to measure resistance by the Wheatstone bridge.The connection between the algorithm and physical test is mediated by a protocol controlling each query, especially the physical time taken by the experimenter. In our studies we find that physical experiments have an exponential time protocol; this we formulate as a general conjecture. Our theory proposes that measurability in Physics is subject to laws which are co-lateral effects of the limits of computability and computational complexity. (shrink)

Since the first edition was published in 1989, Character and Cops has been considered the bible of police ethics training. The book is a comprehensive guide to the ethical challenges faced daily by police officers, especially in times of heightened security. The updated sixth edition features a new foreword by David Bores, a retired lieutenant colonel in the United States military police, and a new chapter titled 'From War Veterans to Peace Officers,' which explores policies for incorporating soldiers returning from (...) Iraq and Afghanistan into the domestic police force. (shrink)

In this study, we explain differences in support for interreligious lawful and violent protests against the religious outgroup. Combining religiosity and social identity approaches, we take three dimensions of religiosity into consideration related to support for interreligious conflict, next to relevant control characteristics. The analysis is based on survey data collected among a random sample of Muslims and Christians across the Indonesian archipelago. Our findings show that members of the Muslim community are, on average, more inclined to support interreligious conflict, (...) both lawful and violent protests. Participation in rites of passage is a crucial aspect of religious practices found to be positively related to both kinds of protest. Religious beliefs show great importance but vary in their influence: particularistic views and intratextual fundamentalism are related to support for lawful protest, whereas religiocentrism is related to support both for lawful and violent protests. In contrast, salience reduces support for violent protest. As such, the findings offer a differentiated way to understand present-day interreligious conflicts among the general population in Indonesia. (shrink)

Originally published in 1931, this book presents a concise biography of the British idealist metaphysician John McTaggart Ellis McTaggart. The text was largely written by the prominent political scientist Goldsworthy Lowes Dickinson, a close friend of the subject. Abundant material from McTaggart's memoirs, letters and other writings is included, with earlier chapters covering more personal areas and later ones focusing on his philosophical approach. Ilustrative figures and notes are also included. This book will be of value to anyone with (...) an interest in McTaggart, metaphysics and British idealism. (shrink)

Television medical dramas frequently depict the practice of medicine and bioethical issues in a strikingly realistic but sometimes inaccurate fashion. Because these shows depict medicine so vividly and are so relevant to the career interests of medical and nursing students, they may affect these students' beliefs, attitudes, and perceptions regarding the practice of medicine and bioethical issues. We conducted a web-based survey of medical and nursing students to determine the medical drama viewing habits and impressions of bioethical issues depicted in (...) them. More than 80% of medical and nursing students watch television medical dramas. Students with more clinical experience tended to have impressions that were more negative than those of students without clinical experience. Furthermore, viewing of television medical dramas is a social event and many students discuss the bioethical issues they observe with friends and family. Television medical dramas may stimulate students to think about and discuss bioethical issues. (shrink)